Initially, several strains that show the action jump from one place / time to another, but after viewing comes the understanding that without these " jumps," the series could be moved into the category of third-rate and quickly forgotten - well, not to be a detective to develop all slow, and the connection between the events would have to show. By genre of this anime, "adventure, history, fantasy," you can add a minimum of drama, mystery, thriller and martial arts.
It all starts back in 1711 on the ship Advena Avis, where the young alchemist Mize Mortillet trying to call a demon, then who gives to all members of the crew of the elixir of immortality, giving the knowledge of its manufacture only Mize.